Genirelix Acetate Injection is prescribed for the inhibition of premature release of luteinizing hormone in women who are undergoing controlled ovarian hyper-stimulation. In fact, Gonadotrope cells release follicle-stimulating hormone and luteinizing hormone in pituitary gland. The natural GnRH bind with receptors on the gonadotrope cells, which results into the secretion of FSH and LH, and production of new GnRH receptors on gonadotropes. Ganirelix Acetate Injection works by blocking natural GnRH from binding to the receptors, thus inducing a quick, reversible suppression of the gonadotropin secretion. It is supplied in a colorless, ready to use solution intended for the subcutaneous administration only. Every prefilled syringe contains 0.1 mg glacial acetic acid, 250 mcg of Ganirelix acetate, 23.5 MG mannitol, and water for the injection adjusted to 5.0 pH level with sodium hydroxide and acetic acid.
It is very easy to administer this medication because mixing is not required. Major benefits offered by the medicine are fewer injections, shorter treatment duration and lesser total medication. The most appropriate sites for the Ganirelix Acetate Injection are abdomen around the navel and upper thigh. In order to remove the surface bacteria, the injection site must be swabbed with disinfectant. Clean about 2 inches around the site where the needle will be inserted and allow the disinfectant dry for one or two minutes before proceeding. You should not take Ganirelix acetate injection if you are pregnant, or if you are allergic to any of its ingredient or gonadotropin releasing hormone. Possible side effects of the medicine include headache, injection site reaction, vaginal bleeding, severe pelvic pain, vomiting and sudden weight gain.
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